GOAT ANTI-RENT1 ANTIBODY

Code: PLA0010-100UL D2-231

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to b...


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Your Price
€484.00 100UL
€595.32 inc. VAT

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Immunogen

The epitope recognized by PLA0010 maps to a region between residue 1075 and the C-terminus (residue 1118) of human Regulator of Nonsense Transcripts 1 (up-frameshift mutation 1 homolog) using the numbering given in entry NP_002902.2 (GeneID 5976).

Other Notes

RENT1, also known as UPF1, is a key regulator of the nonsense-mediated mRNA decay (NMD) pathway. The NMD pathway eliminates mRNAs that prematurely terminate during translation and may serve to protect the cells from dominant-negative effects of truncated proteins, or as a means to regulate protein expression. RENT1 is an ATP-dependent 5’;- 3’; RNA helicase and ATPase that localizes to the cytoplasm and is part of a post-splicing multiprotein complex as well as an mRNA decay complex.

Physical form

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% sodium azide

accession no.NP_002902.2
antibody formaffinity purified immunoglobulin
antibody product typeprimary antibodies
biological sourcegoat
concentration1 mg/mL
Gene Informationgoat ... UPF1(5976)
gradePowered by Bethyl Laboratories, Inc.
Quality Level100
shipped inwet ice
species reactivitymouse, human
storage temp.2-8°C
technique(s)western blot: 1:2,000-1:10000, immunoprecipitation (IP): 2-10 µg/mL
This product has met the following criteria to qualify for the following awards:



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